Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EML4 | Q9HC35 | 4/20 | 0.43 |
| ▸ | ALK | Q9UM73 | 4/20 | 0.43 |
| ▸ | FGFR3 | P22607 | 10/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | RAD52 | P43351 | 1/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.41 |
| ▸ | FGFR2 | P21802 | 2/20 | 0.41 |
| ▸ | FGFR4 | P22455 | 2/20 | 0.41 |
| ▸ | KDR | P35968 | 2/20 | 0.41 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CASP1 | P29466 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CASP7 | P55210 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10127415 | 0.91 | FGFR3 (0.50) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL29399427 | 0.90 | FGFR3 (0.44) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL10036386 | 0.90 | FGFR3 (0.42) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL328446 | 0.90 | FGFR3 (0.44) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL27038804 | 0.89 | EML4 (0.42) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL10036123 | 0.88 | FGFR3 (0.41) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL30879147 | 0.88 | MAPT (0.54) | MAPTKDM4ERAD52ALDH1A1GAA | |
| SCHEMBL10036431 | 0.84 | FGFR3 (0.51) | EML4ALKFGFR3MAPTKDM4E | |
| SCHEMBL16848693 | 0.82 | CD63 (0.43) | MAPTKDM4ERAD52ALDH1A1GAA | |
| SCHEMBL29397031 | 0.81 | KDM4E (0.44) | FGFR3MAPTKDM4ERAD52ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024017258-A1 | EGFR SMALL MOLECULE INHIBITOR, PHARMACEUTICAL COMPOSITION CONTAINING SAME, AND USE THEREOF | 百极弘烨(南通)医药科技有限公司 | 2024-01-25 | — | — | WO | disclosed |