SCHEMBL7140487

SCHEMBL7140487

Nc1cc(Cl)ccc1Oc1ccc(Cl)cc1

nearest known ligand 0.96

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.96
SMN1; SMN2 Q16637 3/20 0.96
CYP1A2 P05177 2/20 0.96
CYP2C9 P11712 2/20 0.96
CYP2C19 P33261 2/20 0.96
ALDH1A1 P00352 2/20 0.96
KDM4E B2RXH2 2/20 0.96
MEN1 O00255 2/20 0.96
KMT2A Q03164 2/20 0.96
CYP2D6 P10635 1/20 0.96
HPGD P15428 1/20 0.96
CYP3A4 P08684 2/20 0.79
HTT P42858 3/20 0.69
LMNA P02545 2/20 0.69
L3MBTL1 Q9Y468 2/20 0.62
MAOA P21397 1/20 0.54
MAOB P27338 1/20 0.54
HTR2A P28223 2/20 0.50
SLC6A4 P31645 2/20 0.50
KCNH2 Q12809 2/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32674568 1.00 MAPT (0.96) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
Hydrochloric Acid SCHEMBL11515445 0.98 MAPT (1.00) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL359771 0.89 SMN1; SMN2 (0.77) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL11409091 0.89 MAPT (0.77) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL307310 0.88 CYP1A2 (1.00) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL11523227 0.88 MAPT (0.76) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL5863619 0.87 MAPT (0.73) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL2967362 0.86 MAPT (0.72) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL13970361 0.85 MAPT (0.71) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19
SCHEMBL641262 0.85 MAPT (0.71) MAPTSMN1; SMN2CYP1A2CYP2C9CYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114179543-B Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技股份有限公司 2023-12-22 CN claimed
CN-114179543-A Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技有限公司 2022-03-15 CN claimed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
CN-114179543-B Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技股份有限公司 2023-12-22 CN disclosed
CN-114179543-A Holographic self-repairing graphene liquid crystal modified polyurethane decorative film and preparation method and application thereof 深圳市深大极光科技有限公司 2022-03-15 CN disclosed
US-9759733-B1 Mass produced, low cost, portable test kit for the detection and identification of narcotics VERITEQUE USA, INC. 2017-09-12 US disclosed
CN-100422137-C Nitrobenzene derivative containing phenoxy and its preparation method WUHNA RUIYANG CHEMICAL CO LTD (CN) 2008-10-01 CN disclosed
CN-1948265-A Nitrobenzene derivative containing phenoxy and its preparation method WUHNA RUIYANG CHEMICAL CO LTD (CN) 2007-04-18 CN disclosed
US-6596907-B1 Halogenating alkoxyphenol; reacting with p-dihalobenzene in presence of copper or salt; etherification; ether fission CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
EP-1119539-B1 A PROCESS FOR THE PREPARATION OF 4,4'-DIHALOGEN-O-HYDROXYDIPHENYL COMPOUNDS CIBA SC HOLDING AG (CH) 2003-02-26 EP disclosed
US-20020128522-A1 Process for the preparation of 4,4' -dihalogen-o-hydroxydiphenyl compounds TEODORO ARMANDO DI (DE) 2002-09-12 US disclosed
US-4221714-A ANTI-PSYCHOTIC AGENTS AMERICAN CYANAMID COMPANY (US) 1980-09-09 US disclosed
EP-0008627-A2 Quinazoline derivatives, azo dyes derived from the quinazolines and their use as pigments BAYER AG (DE) 1980-03-19 EP disclosed
US-4183727-A Process for the production of water-insoluble azo dyestuffs on the fiber HOECHST AKTIENGESELLSCHAFT (DE) 1980-01-15 US disclosed
US-4168952-A ACETOACETIC ACID ARYLAMIDE AS COUPLER HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-09-25 US disclosed
US-4165967-A HYDROXY-PYRIDINE OR PYRIDONE COUPLERS HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) 1979-08-28 US disclosed
US-4162893-A Process for dyeing human hair with diazo salts HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (HENKEL KGAA) (DE) 1979-07-31 US disclosed
US-4065254-A DIAZO DYES, LEATHER, COTTON, WOOL CIBA-GEIGY CORPORATION (US) 1977-12-27 US disclosed
US-4014863-A LACQUERS, PRINTING INKS, PAINTS BAYER AKTIENGESELLSCHAFT (DT) 1977-03-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020128522-A1 Process for the preparation of 4,4' -dihalogen-o-hydroxydiphenyl compounds DDT, CYP2F1, CYP4X1 MAPT 3818/4885SMN1; SMN2 4637/4885CYP1A2 75/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.