Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAO | P14920 | 2/20 | 0.44 |
| ▸ | PRKCI | P41743 | 1/20 | 0.43 |
| ▸ | NUDT1 | P36639 | 4/20 | 0.41 |
| ▸ | IDO1 | P14902 | 3/20 | 0.40 |
| ▸ | TDO2 | P48775 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | CCNK | O75909 | 1/20 | 0.38 |
| ▸ | CDK12 | Q9NYV4 | 1/20 | 0.38 |
| ▸ | BRAF | P15056 | 2/20 | 0.38 |
| ▸ | TNNI3K | Q59H18 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22554070 | 1.00 | DAO (0.44) | DAOPRKCINUDT1IDO1TDO2 | |
| SCHEMBL22554309 | 0.83 | ABL1 (0.44) | DAOPRKCINUDT1 | |
| SCHEMBL30731054 | 0.83 | ABL1 (0.44) | DAOPRKCINUDT1 | |
| SCHEMBL7976646 | 0.81 | DAO (0.45) | DAONUDT1IDO1TDO2KDM4E | |
| SCHEMBL22554098 | 0.81 | DAO (0.45) | DAONUDT1CCNKCDK12 | |
| SCHEMBL23147745 | 0.80 | NUDT1 (0.44) | DAONUDT1IDO1TDO2KDM4E | |
| SCHEMBL20839678 | 0.80 | GRIN1 (0.46) | DAOPRKCINUDT1IDO1TDO2 | |
| SCHEMBL3008612 | 0.80 | IDO1 (0.49) | DAONUDT1IDO1TDO2KDM4E | |
| SCHEMBL29722004 | 0.80 | IDO1 (0.49) | DAONUDT1IDO1TDO2KDM4E | |
| SCHEMBL29721792 | 0.80 | NUDT1 (0.44) | DAONUDT1IDO1TDO2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112088157-B | Aryl-bipyridylamine derivatives as phosphatidylinositol phosphokinase inhibitors | 拉文纳制药公司 | 2023-12-26 | — | — | CN | disclosed |