Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRMT5 | O14744 | 9/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.38 |
| ▸ | YAP1 | P46937 | 3/20 | 0.35 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.34 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26924596 | 1.00 | PRMT5 (0.38) | PRMT5GPR119YAP1WDR77L3MBTL1 | |
| SCHEMBL30732110 | 1.00 | PRMT5 (0.38) | PRMT5GPR119YAP1WDR77L3MBTL1 | |
| SCHEMBL30731978 | 1.00 | PRMT5 (0.38) | PRMT5GPR119YAP1WDR77L3MBTL1 | |
| SCHEMBL26925786 | 0.92 | HTR3A (0.35) | PRMT5GPR119LNPEP | |
| SCHEMBL26925784 | 0.92 | HTR3A (0.35) | PRMT5GPR119LNPEP | |
| SCHEMBL26926987 | 0.92 | HTR3A (0.35) | PRMT5GPR119LNPEP | |
| SCHEMBL31434035 | 0.90 | TNF (0.38) | PRMT5GPR119YAP1L3MBTL1MEN1 | |
| SCHEMBL23541116 | 0.89 | NAMPT (0.41) | PRMT5GPR119WDR77BRD4LNPEP | |
| SCHEMBL30026597 | 0.89 | NAMPT (0.41) | PRMT5GPR119WDR77BRD4LNPEP | |
| SCHEMBL30732266 | 0.88 | PRMT5 (0.38) | PRMT5GPR119YAP1WDR77MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |