Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.36 |
| ▸ | PRMT5 | O14744 | 5/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.35 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.35 |
| ▸ | TNK2 | Q07912 | 1/20 | 0.35 |
| ▸ | KIT | P10721 | 1/20 | 0.34 |
| ▸ | BTK | Q06187 | 2/20 | 0.34 |
| ▸ | NAMPT | P43490 | 1/20 | 0.34 |
| ▸ | HTR6 | P50406 | 1/20 | 0.34 |
| ▸ | JAK1 | P23458 | 1/20 | 0.34 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.34 |
| ▸ | KHK | P50053 | 1/20 | 0.34 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30732135 | 1.00 | GPR119 (0.39) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL30732290 | 1.00 | GPR119 (0.39) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL30732183 | 1.00 | GPR119 (0.39) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL31433749 | 0.95 | KDM1A (0.37) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL26925891 | 0.93 | KHK (0.36) | GPR119PRMT5LNPEPBTKNAMPT | |
| SCHEMBL26924678 | 0.93 | KHK (0.36) | GPR119PRMT5LNPEPBTKNAMPT | |
| SCHEMBL26925704 | 0.93 | KHK (0.36) | GPR119PRMT5LNPEPBTKNAMPT | |
| SCHEMBL23541116 | 0.91 | NAMPT (0.41) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL30026597 | 0.91 | NAMPT (0.41) | GPR119BRD4PRMT5WDR77LNPEP | |
| SCHEMBL31433535 | 0.90 | TNF (0.39) | GPR119BTKHTR6JAK1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4536650-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-04-16 | — | — | EP | disclosed |
| WO-2023240038-A1 | TRICYCLIC QUINOLONE BCL6 BIFUNCTIONAL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-12-14 | — | — | WO | disclosed |