Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 16/20 | 0.53 |
| ▸ | TLR7 | Q9NYK1 | 9/20 | 0.47 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26695843 | 1.00 | TLR8 (0.53) | TLR8TLR7NUDT1CYP2D6CYP2C19 | |
| SCHEMBL26695833 | 0.87 | KMT2A (0.41) | TLR8TLR7 | |
| SCHEMBL30733442 | 0.87 | KMT2A (0.41) | TLR8TLR7 | |
| SCHEMBL30733394 | 0.84 | SMN1; SMN2 (0.39) | TLR8TLR7NUDT1 | |
| SCHEMBL26695905 | 0.84 | SMN1; SMN2 (0.39) | TLR8TLR7NUDT1 | |
| SCHEMBL8053396 | 0.77 | TLR8 (0.46) | TLR8TLR7NUDT1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8038529 | 0.75 | TLR8 (0.44) | TLR8TLR7NUDT1CYP2D6CYP2C19 | |
| SCHEMBL8056016 | 0.72 | TLR8 (0.48) | TLR8TLR7NUDT1CYP2D6CYP2C19 | |
| Hydrochloric Acid SCHEMBL8038827 | 0.71 | TLR8 (0.47) | TLR8TLR7NUDT1CYP2D6CYP2C19 | |
| SCHEMBL11752787 | 0.70 | TLR8 (0.73) | TLR8TLR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117425660-A | Aromatic heterocyclic compound, intermediate thereof, pharmaceutical composition and application | 上海翊石医药科技有限公司 | 2024-01-19 | — | — | CN | disclosed |