SCHEMBL30733451

SCHEMBL30733451

CCCCCCCCCCCCCCCCCCOCCOC1C(O)C(COC(c2ccccc2)(c2ccc(OC)cc2)c2ccc(OC)cc2)OC1n1ccc(=O)[nH]c1=O

nearest known ligand 0.46

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
TYMP P19971 2/20 0.46
P2RY14 Q15391 3/20 0.44
P2RY2 P41231 6/20 0.40
P2RY12 Q9H244 2/20 0.40
P2RY6 Q15077 3/20 0.40
P2RY1 P47900 2/20 0.39
B4GALT1 P15291 1/20 0.39
P2RY4 P51582 2/20 0.38
DUT P33316 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30733470 1.00 TYMP (0.46) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL30733452 0.96 TYMP (0.43) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL31093241 0.96 TYMP (0.48) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL6930639 0.96 TYMP (0.48) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL6930638 0.96 TYMP (0.48) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL7913274 0.96 TYMP (0.48) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL6930000 0.95 TYMP (0.49) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL30733453 0.94 TYMP (0.46) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL30733465 0.94 TYMP (0.46) TYMPP2RY14P2RY2P2RY12P2RY6
SCHEMBL7553293 0.91 TYMP (0.51) TYMPP2RY14P2RY2P2RY6P2RY4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382324-A1 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2025-12-18 US disclosed
EP-4547852-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES Alnylam Pharmaceuticals, Inc. (US) 2025-05-07 EP disclosed
WO-2024006953-A2 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES ALNYLAM PHARMACEUTICALS, INC. (US) 2024-01-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250382324-A1 MONOMERS AND METHODS FOR SYNTHESIS OF MODIFIED OLIGONUCLEOTIDES POLM, PCNA, POLRMT TYMP 83/4885P2RY14 3785/4885P2RY2 4545/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.