Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3BCHECHRM1CHRM2CHRM3CHRM4CHRNA3CHRNA4CHRNB2CHRNB4ESR1ESR2GABRA1GABRB1GABRG2GBA1GHSRHRH1HTR1DHTR2AMAOBOPRD1OPRK1OPRM1SLC6A2SLC6A3TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8UGCGrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Cadaverine Tartrate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 9/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.42 |
| ▸ | OPRL1 | P41146 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tartaric Acid SCHEMBL30733603 | 1.00 | TAAR1 (0.48) | TAAR1HTR1ADRD2HTR7OPRL1 | |
| Cadaverine Tartrate SCHEMBL29223353 | 1.00 | TAAR1 (0.48) | TAAR1HTR1ADRD2HTR7OPRL1 | |
| Cadaverine Tartrate SCHEMBL28523054 | 1.00 | TAAR1 (0.48) | TAAR1HTR1ADRD2HTR7OPRL1 | |
| Mandelic Acid SCHEMBL30733602 | 0.87 | TAAR1 (0.43) | TAAR1HTR1ADRD2HTR7OPRL1 | |
| Malic Acid SCHEMBL29140406 | 0.87 | TAAR1 (0.46) | TAAR1HTR1ADRD2HTR7OPRL1 | |
| SCHEMBL28511084 | 0.86 | TAAR1 (0.60) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL28511085 | 0.86 | TAAR1 (0.60) | TAAR1HTR1ADRD2HTR7 | |
| SCHEMBL30733601 | 0.86 | TAAR1 (0.60) | TAAR1HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL28522435 | 0.85 | TAAR1 (0.59) | TAAR1HTR1ADRD2HTR7 | |
| Hydrochloric Acid SCHEMBL28513760 | 0.85 | TAAR1 (0.59) | TAAR1HTR1ADRD2HTR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118406063-A | Salt, crystal forms and preparation method thereof | 赛诺维信制药公司 | 2024-07-30 | — | — | CN | claimed |
| CN-118406063-A | Salt, crystal forms and preparation method thereof | 赛诺维信制药公司 | 2024-07-30 | — | — | CN | disclosed |
| CN-112135827-B | Salt, crystal forms and preparation method thereof | 赛诺维信制药公司 | 2024-01-12 | — | — | CN | disclosed |