Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.33 |
| ▸ | BTK | Q06187 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.31 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20918704 | 0.86 | HRH3 (0.42) | HPGDHRH3BTKEPHX1GPR119 | |
| SCHEMBL28114737 | 0.84 | HRH3 (0.40) | HPGDHRH3BTKEPHX1GPR119 | |
| SCHEMBL2633813 | 0.83 | HRH3 (0.42) | HPGDHRH3BTKEPHX1GPR119 | |
| SCHEMBL27713683 | 0.83 | HPGD (0.40) | HPGDHRH3BTKEPHX1RECQL | |
| SCHEMBL28481377 | 0.83 | BTK (0.44) | HPGDHRH3BTKEPHX1RECQL | |
| SCHEMBL2223446 | 0.81 | HRH3 (0.41) | HPGDHRH3BTKEPHX1GPR119 | |
| SCHEMBL23293551 | 0.81 | HPGD (0.42) | HPGDHRH3BTKEPHX1RECQL | |
| SCHEMBL12002951 | 0.79 | HRH3 (0.44) | HPGDHRH3BTKEPHX1GPR119 | |
| SCHEMBL30415219 | 0.77 | HRH3 (0.39) | HPGDHRH3BTK | |
| SCHEMBL25277997 | 0.77 | HRH3 (0.37) | HPGDHRH3BTKEPHX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519273-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |