Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.34 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | PTPN6 | P29350 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28481377 | 0.94 | BTK (0.44) | HRH3HPGDRECQLCHRM2CHRM1 | |
| SCHEMBL27713683 | 0.94 | HPGD (0.40) | HRH3HPGDRECQLBTKKMT2A | |
| SCHEMBL23293551 | 0.92 | HPGD (0.42) | HRH3HPGDRECQLBTKKMT2A | |
| SCHEMBL1514914 | 0.89 | TSHR (0.41) | HRH3HPGDRECQLBTKKMT2A | |
| SCHEMBL30733879 | 0.84 | HPGD (0.35) | HRH3HPGDRECQLBTKEPHX1 | |
| SCHEMBL2561899 | 0.84 | CHRNB2 (0.36) | HRH3HPGDRECQLKMT2AMEN1 | |
| SCHEMBL1295721 | 0.83 | HRH3 (0.51) | HRH3HPGDRECQLCHRM2CHRM1 | |
| SCHEMBL28492122 | 0.83 | HRH3 (0.51) | HRH3HPGDRECQLCHRM2CHRM1 | |
| SCHEMBL186721 | 0.83 | HRH3 (0.51) | HRH3HPGDRECQLCHRM2CHRM1 | |
| SCHEMBL23727397 | 0.83 | TSHR (0.36) | HRH3HPGDRECQLBTKKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118355020-A | Therapeutic compounds for HIV virus infection | 吉利德科学公司 | 2024-07-16 | — | — | CN | disclosed |
| CN-114423740-A | Pyrazole derivatives for controlling arthropods | 拜耳动物保健有限责任公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-113509557-A | Targeted protease degradation platform (TED) | 嘉兴优博生物技术有限公司 | 2021-10-19 | — | — | CN | disclosed |
| CN-111454188-A | Cyclopropylamines as L SD1inhibitors | 因赛特公司 | 2020-07-28 | — | — | CN | disclosed |
| CN-111356456-A | 2-arylsulfonamido-iV-arylacetamide derived Stat3 inhibitor | 夏威夷大学 | 2020-06-30 | — | — | CN | disclosed |
| CN-106164066-B | Cyclopropylamines as LSD1inhibitors | 因赛特公司 | 2020-01-17 | — | — | CN | disclosed |
| CN-106164066-A | Cyclopropylamines as lsd1 inhibitors | 因赛特公司 | 2016-11-23 | — | — | CN | disclosed |