Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 20/20 | 0.52 |
| ▸ | CRBN | Q96SW2 | 20/20 | 0.52 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635102 | 0.87 | DDB1 (0.55) | DDB1CRBNIKZF3 | |
| SCHEMBL30733871 | 0.87 | CRBN (0.46) | DDB1CRBNIKZF3 | |
| SCHEMBL31003844 | 0.87 | DDB1 (0.47) | DDB1CRBN | |
| SCHEMBL23915105 | 0.81 | DDB1 (0.62) | DDB1CRBNIKZF3 | |
| SCHEMBL21759957 | 0.80 | DDB1 (0.67) | DDB1CRBNIKZF3 | |
| SCHEMBL22790728 | 0.80 | DDB1 (0.67) | DDB1CRBNIKZF3 | |
| SCHEMBL22525688 | 0.80 | DDB1 (0.67) | DDB1CRBNIKZF3 | |
| SCHEMBL23945888 | 0.80 | CRBN (0.52) | DDB1CRBNIKZF3 | |
| SCHEMBL26635125 | 0.80 | DDB1 (0.55) | DDB1CRBNIKZF3 | |
| SCHEMBL21069260 | 0.80 | DDB1 (0.66) | DDB1CRBNIKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519273-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |