Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 15/20 | 0.46 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.46 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.34 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.33 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.33 |
| ▸ | IKZF3 | Q9UKT9 | 3/20 | 0.33 |
| ▸ | IKZF2 | Q9UKS7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26635128 | 0.90 | CRBN (0.48) | CRBNDDB1IRAK4BRD9IKZF3 | |
| SCHEMBL21997642 | 0.90 | CRBN (0.48) | CRBNDDB1IRAK4BRD9IKZF3 | |
| SCHEMBL21997673 | 0.88 | GPR119 (0.44) | CRBNDDB1BRD9 | |
| SCHEMBL26634892 | 0.88 | GPR119 (0.44) | CRBNDDB1BRD9 | |
| SCHEMBL30733916 | 0.87 | DDB1 (0.52) | CRBNDDB1IKZF3 | |
| SCHEMBL26850676 | 0.82 | DDB1 (0.48) | CRBNDDB1IKZF3 | |
| SCHEMBL30733857 | 0.82 | DDB1 (0.48) | CRBNDDB1IKZF3 | |
| SCHEMBL26850661 | 0.82 | GPR119 (0.42) | CRBNDDB1 | |
| SCHEMBL31003947 | 0.82 | GPR119 (0.42) | CRBNDDB1 | |
| SCHEMBL26634965 | 0.82 | CRBN (0.52) | CRBNDDB1IKZF1IKZF3IKZF2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519273-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | Paq Therapeutics Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215906-A1 | KRAS G12D PROTEOLYSIS TARGETING CHIMERAS | HANGZHOU JIJING PHARMACEUTICALTECHNOLOGY LIMITED (CN) | 2023-11-09 | — | — | WO | disclosed |