Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.57 |
| ▸ | BACE1 | P56817 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 14/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 13/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.56 |
| ▸ | CLK4 | Q9HAZ1 | 11/20 | 0.56 |
| ▸ | MEN1 | O00255 | 8/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 8/20 | 0.56 |
| ▸ | MAPK1 | P28482 | 8/20 | 0.56 |
| ▸ | LMNA | P02545 | 7/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 7/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 11/20 | 0.52 |
| ▸ | USP2 | O75604 | 7/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 7/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | EGFR | P00533 | 1/20 | 0.50 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.50 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30734172 | 0.83 | ACHE (0.59) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734227 | 0.81 | ACHE (0.57) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734210 | 0.81 | ACHE (0.56) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734203 | 0.81 | ACHE (0.56) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL31745219 | 0.78 | ACHE (0.53) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL31745382 | 0.78 | ACHE (0.53) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734194 | 0.77 | HTT (0.66) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734213 | 0.76 | ACHE (0.57) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 | |
| SCHEMBL30734132 | 0.76 | HRH4 (0.66) | ACHEBACE1CYP1A2ALDH1A1MEN1 | |
| SCHEMBL30734186 | 0.76 | ACHE (0.60) | ACHEBACE1CYP3A4CYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543888-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | Arizona Board of Regents on behalf of The University of Arizona (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250083-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |