Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.48 |
| ▸ | KIT | P10721 | 3/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.46 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.44 |
| ▸ | JAK3 | P52333 | 2/20 | 0.44 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.43 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | BACE1 | P56817 | 2/20 | 0.41 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.40 |
| ▸ | FLT3 | P36888 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | RET | P07949 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25422069 | 0.95 | HTT (0.49) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL30405762 | 0.95 | HTT (0.49) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL30902204 | 0.94 | HTT (0.48) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL30902146 | 0.94 | HTT (0.48) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL30902102 | 0.91 | HTT (0.52) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL31029554 | 0.91 | HTT (0.52) | HTTKITNPSR1ALDH1A1CYP11B2 | |
| SCHEMBL30902259 | 0.87 | HTT (0.61) | HTTKITNPSR1ALDH1A1PDGFRB | |
| SCHEMBL2798395 | 0.87 | HTT (0.61) | HTTKITNPSR1ALDH1A1PDGFRB | |
| SCHEMBL30398383 | 0.83 | JAK3 (0.54) | HTTKITNPSR1ALDH1A1PDGFRB | |
| SCHEMBL26176358 | 0.83 | JAK3 (0.54) | HTTKITNPSR1ALDH1A1PDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543888-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | Arizona Board of Regents on behalf of The University of Arizona (US) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023250083-A1 | SMALL MOLECULE INHIBITORS OF DYRK/CLK AND USES THEREOF | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-12-28 | — | — | WO | disclosed |