Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.58 |
| ▸ | KIT | P10721 | 3/20 | 0.57 |
| ▸ | PDGFRB | P09619 | 6/20 | 0.56 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.53 |
| ▸ | PDGFRA | P16234 | 4/20 | 0.52 |
| ▸ | FLT3 | P36888 | 1/20 | 0.52 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.50 |
| ▸ | BACE1 | P56817 | 4/20 | 0.49 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2798395 | 1.00 | HTT (0.61) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL30902159 | 0.91 | KIT (0.57) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL30902102 | 0.88 | HTT (0.52) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL31029554 | 0.88 | HTT (0.52) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL30405762 | 0.88 | HTT (0.49) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL25422069 | 0.88 | HTT (0.49) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL30734201 | 0.87 | HTT (0.48) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL2794112 | 0.87 | KIT (0.59) | KITPDGFRBMAP4K4PDGFRAMTNR1B | |
| SCHEMBL30902204 | 0.85 | HTT (0.48) | HTTALDH1A1NPSR1KITPDGFRB | |
| SCHEMBL30902146 | 0.85 | HTT (0.48) | HTTALDH1A1NPSR1KITPDGFRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117957219-A | Pyridine derivative and application thereof | 四川汇宇制药股份有限公司 | 2024-04-30 | — | — | CN | disclosed |