Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 6/20 | 0.38 |
| ▸ | MAPT | P10636 | 6/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.38 |
| ▸ | RAB9A | P51151 | 4/20 | 0.38 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 6/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTR1B | P28222 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26637328 | 1.00 | HPGD (0.38) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL26636377 | 1.00 | HPGD (0.38) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL26637101 | 1.00 | HPGD (0.38) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL26635946 | 1.00 | HPGD (0.38) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL30735422 | 1.00 | HPGD (0.38) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL30734478 | 0.80 | ALDH1A1 (0.44) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL30734973 | 0.80 | ALDH1A1 (0.44) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL30735065 | 0.80 | ALDH1A1 (0.44) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL26635859 | 0.80 | ALDH1A1 (0.44) | HPGDMAPTL3MBTL1RAB9ANPC1 | |
| SCHEMBL26636376 | 0.80 | ALDH1A1 (0.44) | HPGDMAPTL3MBTL1RAB9ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4519259-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2025-03-12 | — | — | EP | disclosed |
| WO-2023215482-A1 | TETRAHYDROISOQUINOLINE HETEROBIFUNCTIONAL BCL-XL DEGRADERS | Treeline Biosciences, Inc. (US) | 2023-11-09 | — | — | WO | disclosed |