Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.68 |
| ▸ | AKR1C3 | P42330 | 9/20 | 0.64 |
| ▸ | MEP1B | Q16820 | 2/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | IL1RN | P18510 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29123951 | 1.00 | CYP2C19 (0.68) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL29123974 | 0.86 | TDP1 (0.56) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL29123957 | 0.84 | PKM (0.66) | TDP1ALDH1A1LMNA | |
| SCHEMBL2850488 | 0.83 | GAA (0.55) | CYP2C19TDP1MAPK1 | |
| SCHEMBL30735480 | 0.83 | TDP1 (0.53) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL2854994 | 0.82 | GAA (0.57) | CYP2C19TDP1MAPK1KMT2A | |
| SCHEMBL1017949 | 0.81 | CYP2C19 (1.00) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL30735530 | 0.81 | TDP1 (0.52) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL30866646 | 0.80 | CYP2C19 (0.76) | CYP2C19AKR1C3MEP1BTDP1MAPK1 | |
| SCHEMBL13614830 | 0.80 | CYP2C19 (0.76) | CYP2C19AKR1C3MEP1BTDP1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117229257-A | Meta-sulfamoyl benzamide compound and preparation method, pharmaceutical composition and application thereof | 中国药科大学 | 2023-12-15 | — | — | CN | disclosed |