⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL762914 | 1.00 | — | — | |
| SCHEMBL29690486 | 0.80 | — | — | |
| SCHEMBL342702 | 0.80 | — | — | |
| SCHEMBL2489172 | 0.79 | — | — | |
| SCHEMBL1126105 | 0.79 | — | — | |
| SCHEMBL29426953 | 0.79 | — | — | |
| SCHEMBL31180717 | 0.79 | — | — | |
| SCHEMBL305800 | 0.75 | — | — | |
| SCHEMBL15901334 | 0.75 | — | — | |
| SCHEMBL4058192 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543881-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | Engine Biosciences Pte. Ltd. (SG) | 2025-04-30 | — | — | EP | disclosed |
| CN-118791480-A | Heteroaromatic ring compounds and application thereof | 上海艾力斯医药科技股份有限公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118239947-A | Compound, intermediate, preparation method, pharmaceutical composition and application | 上海艾力斯医药科技股份有限公司 | 2024-06-25 | — | — | CN | disclosed |
| WO-2023249563-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-12-28 | — | — | WO | disclosed |