⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2489172 | 1.00 | — | — | |
| SCHEMBL30735720 | 0.79 | — | — | |
| SCHEMBL762914 | 0.79 | — | — | |
| SCHEMBL29393219 | 0.79 | — | — | |
| SCHEMBL390289 | 0.79 | — | — | |
| SCHEMBL23820848 | 0.75 | — | — | |
| SCHEMBL761547 | 0.75 | — | — | |
| SCHEMBL15901334 | 0.75 | — | — | |
| SCHEMBL1506656 | 0.75 | — | — | |
| SCHEMBL305800 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4658656-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | Beone Medicines I GmbH (CH) | 2025-12-10 | — | — | EP | disclosed |
| WO-2025106949-A1 | WRN INHIBITORS | RADD PHARMACEUTICALS, INC. (US) | 2025-05-22 | — | — | WO | disclosed |
| WO-2024160276-A1 | CONDENSED HETEROCYCLIC COMPOUNDS AS INHIBITOR OF DIACYLGLYCEROL KINASES | BEIGENE, LTD. (KY) | 2024-08-08 | — | — | WO | disclosed |
| CN-118440071-A | Inhibitor of apoptosis signal regulating kinase 1 and application thereof | 中国人民解放军海军军医大学 | 2024-08-06 | — | — | CN | disclosed |
| CN-118290328-A | Hydrocarbon pyridine and preparation method thereof | 北京师范大学 | 2024-07-05 | — | — | CN | disclosed |
| CN-116891468-A | Thiazole compound and application thereof | 南京再明医药有限公司 | 2023-10-17 | — | — | CN | disclosed |
| EP-4217062-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN Pharmaceutica NV (BE) | 2023-08-02 | — | — | EP | disclosed |
| CN-116323557-A | Cyclobutylamide monoacylglycerol lipase modulators | 詹森药业有限公司 | 2023-06-23 | — | — | CN | disclosed |
| CN-111527090-B | Pyrazolo-pyrrolo-pyrimidine-dione derivatives as P2X3 inhibitors | 拜耳公司 | 2023-05-26 | — | — | CN | disclosed |
| CN-110546149-B | Piperidines as PCSK9 inhibitors | 深圳信立泰药业股份有限公司 | 2022-11-11 | — | — | CN | disclosed |
| CN-111333626-B | Phenyl pyrrolidine compounds and uses thereof | 武汉人福创新药物研发中心有限公司 | 2022-10-18 | — | — | CN | disclosed |
| CN-107922347-B | Novel imide derivatives and their use as pharmaceuticals | 田边三菱制药株式会社 | 2022-06-28 | — | — | CN | disclosed |
| WO-2022063784-A1 | CYCLOBUTYL AMIDE MONOACYLGLYCEROL LIPASE MODULATORS | JANSSEN PHARMACEUTICA NV (BE) | 2022-03-31 | — | — | WO | disclosed |