Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | VRK1 | Q99986 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25205318 | 0.77 | VRK1 (0.33) | VRK1 | |
| SCHEMBL9939110 | 0.77 | DAO (0.37) | VRK1 | |
| SCHEMBL31015996 | 0.77 | VRK1 (0.33) | VRK1 | |
| SCHEMBL31409706 | 0.74 | KDM4E (0.32) | VRK1 | |
| SCHEMBL8123778 | 0.74 | VRK1 (0.32) | VRK1 | |
| SCHEMBL25928162 | 0.71 | VRK1 (0.30) | VRK1 | |
| SCHEMBL25938566 | 0.71 | VRK1 (0.30) | VRK1 | |
| SCHEMBL18899552 | 0.68 | LMNA (0.34) | — | |
| SCHEMBL25928185 | 0.67 | VRK1 (0.30) | VRK1 | |
| SCHEMBL11207268 | 0.66 | NPC1 (0.31) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4543881-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | Engine Biosciences Pte. Ltd. (SG) | 2025-04-30 | — | — | EP | disclosed |
| WO-2023249563-A1 | COMPOUNDS AND METHOD FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2023-12-28 | — | — | WO | disclosed |