Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | WHR1 | P49842 | 1/20 | 0.41 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | SOS2 | Q07890 | 1/20 | 0.38 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | KDM1A | O60341 | 1/20 | 0.37 |
| ▸ | EHMT2 | Q96KQ7 | 1/20 | 0.37 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAD52 | P43351 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27342913 | 0.88 | KMT2A (0.44) | KMT2AWHR1CHEK2SOS2KDM4E | |
| SCHEMBL27343469 | 0.87 | KMT2A (0.43) | KMT2AWHR1CHEK2SOS2KCNH2 | |
| SCHEMBL27343467 | 0.84 | KMT2A (0.41) | KMT2AWHR1CHEK2KDM1AEHMT2 | |
| SCHEMBL27343346 | 0.79 | LMNA (0.47) | KMT2AWHR1RAB9AALDH1A1HPGD | |
| SCHEMBL30736052 | 0.76 | CHEK2 (0.42) | WHR1CHEK2RAB9AALDH1A1HPGD | |
| SCHEMBL27342922 | 0.76 | CHEK2 (0.42) | WHR1CHEK2RAB9AALDH1A1HPGD | |
| SCHEMBL27343609 | 0.76 | EPHX1 (0.51) | KMT2ARAB9AKDM4EALDH1A1HSD17B10 | |
| SCHEMBL27343475 | 0.75 | KDM4E (0.38) | KMT2ACHEK2KDM4EALDH1A1HPGD | |
| SCHEMBL30736177 | 0.75 | KDM4E (0.39) | KMT2ARAB9ASOS2KDM4EALDH1A1 | |
| SCHEMBL27343474 | 0.75 | KDM4E (0.39) | KMT2ARAB9ASOS2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024003535-A2 | COMPOUNDS | UNIVERSITY OF DUNDEE (GB) | 2024-01-04 | — | — | WO | disclosed |