Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.36 |
| ▸ | MAPK8 | P45983 | 4/20 | 0.33 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.30 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5044441 | 0.69 | — | — | |
| SCHEMBL29759466 | 0.67 | IRAK4 (0.38) | ALDH1A1MAPTMEN1MAPK1KMT2A | |
| Hydrochloric Acid SCHEMBL30566533 | 0.66 | IRAK4 (0.37) | ALDH1A1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL21958623 | 0.64 | ALDH1A1 (0.46) | ALDH1A1MAPTMEN1MAPK1KMT2A | |
| SCHEMBL2631222 | 0.63 | MAPT (0.42) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL18933589 | 0.63 | — | — | |
| SCHEMBL29882577 | 0.61 | PARP1 (0.38) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| Hydrochloric Acid SCHEMBL16468136 | 0.61 | KDM4E (0.41) | ALDH1A1MAPTMEN1KMT2AHSD17B10 | |
| SCHEMBL4423753 | 0.60 | TP53 (0.43) | ALDH1A1MAPTKMT2AHSD17B10KDM4E | |
| SCHEMBL21955856 | 0.60 | MEN1 (0.46) | ALDH1A1MAPTMEN1MAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547669-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-05-07 | — | — | EP | disclosed |
| WO-2024002157-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-01-04 | — | — | WO | disclosed |