Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.38 |
| ▸ | CHUK | O15111 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 5/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
| ▸ | MAP2K3 | P46734 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | CLK1 | P49759 | 1/20 | 0.33 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3796726 | 0.75 | SIRT3 (0.44) | SIRT3TDP1TBXAS1CHUKKDM4E | |
| SCHEMBL2631222 | 0.72 | MAPT (0.42) | TDP1KDM4EMAP2K3CYP3A4CYP2C19 | |
| SCHEMBL5489397 | 0.71 | IDO1 (0.36) | CDC7CYP2D6MAPK1CYP11B2ALDH1A1 | |
| Hydrochloric Acid SCHEMBL16468136 | 0.70 | KDM4E (0.41) | TDP1KDM4EMAP2K3CYP3A4CYP2C19 | |
| SCHEMBL19555308 | 0.70 | MKNK1 (0.37) | SIRT3TDP1TBXAS1KDM4ECYP1A2 | |
| SCHEMBL17729406 | 0.68 | IRAK4 (0.45) | SIRT3TDP1KDM4EHTTALDH1A1 | |
| SCHEMBL27985185 | 0.67 | KDM4E (0.45) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL29882577 | 0.67 | PARP1 (0.38) | TDP1CHUKKDM4ECLK1DYRK1A | |
| Hydrochloric Acid SCHEMBL28110444 | 0.66 | KDM4E (0.43) | KDM4EALDH1A1HPGDTSHRHSD17B10 | |
| SCHEMBL30736072 | 0.66 | SIRT3 (0.39) | SIRT3TDP1CLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4547669-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | Insilico Medicine IP Limited (HK) | 2025-05-07 | — | — | EP | disclosed |
| CN-119451964-A | FGFR2 and FGFR3 inhibitors and uses thereof | 英矽智能科技知识产权有限公司 | 2025-02-14 | — | — | CN | disclosed |
| WO-2024002157-A1 | INHIBITORS OF FGFR2 AND FGFR3 AND USES THEREOF | INSILICO MEDICINE IP LIMITED (CN) | 2024-01-04 | — | — | WO | disclosed |