Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NR2F2 | P24468 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.38 |
| ▸ | XBP1 | P17861 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21591923 | 1.00 | SYK (0.47) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21591880 | 0.92 | SYK (0.47) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL30736356 | 0.92 | SYK (0.47) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21591870 | 0.88 | MEN1 (0.42) | NPSR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21591869 | 0.88 | MEN1 (0.42) | NPSR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21593641 | 0.88 | MEN1 (0.42) | NPSR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL21593692 | 0.88 | SYK (0.49) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL30736359 | 0.88 | SYK (0.49) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL21593645 | 0.88 | SYK (0.49) | SYKNPSR1MEN1KMT2AALDH1A1 | |
| SCHEMBL30736383 | 0.88 | SYK (0.49) | SYKNPSR1MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112236431-B | Purinone Compounds and Their Use in the Treatment of Cancer | 阿斯利康(瑞典)有限公司 | 2024-02-13 | — | — | CN | disclosed |