Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.69 |
| ▸ | MEN1 | O00255 | 2/20 | 0.69 |
| ▸ | TSHR | P16473 | 2/20 | 0.69 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.69 |
| ▸ | LMNA | P02545 | 1/20 | 0.69 |
| ▸ | MPO | P05164 | 1/20 | 0.69 |
| ▸ | BLM | P54132 | 1/20 | 0.69 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.69 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.69 |
| ▸ | KCNT1 | Q5JUK3 | 1/20 | 0.61 |
| ▸ | EGFR | P00533 | 2/20 | 0.59 |
| ▸ | SRC | P12931 | 1/20 | 0.59 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.56 |
| ▸ | BRS3 | P32247 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL901463 | 1.00 | MAPT (0.69) | MAPTKDM4EMEN1TSHRKMT2A | |
| Hydrochloric Acid SCHEMBL9834221 | 0.99 | MAPT (0.67) | MAPTKDM4EMEN1TSHRKMT2A | |
| Trifluoroacetic Acid SCHEMBL14762748 | 0.93 | MAPT (0.60) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL8689585 | 0.90 | HDAC8 (0.63) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL7613225 | 0.90 | KMT2A (0.60) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL8689774 | 0.90 | MAPT (0.63) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL8689768 | 0.90 | MAPT (0.63) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL8398098 | 0.90 | KDM4E (0.60) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL10691172 | 0.90 | MAPT (0.60) | MAPTKDM4EMEN1TSHRKMT2A | |
| SCHEMBL8689596 | 0.90 | HDAC8 (0.63) | MAPTKDM4EMEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023247999-A1 | PEPTIDIC PAIN MODULATORS AND METHODS FOR PRODUCING AND USING THE SAME | MAINLINE BIOSCIENCES (SHANGHAI) CO., LTD. (CN) | 2023-12-28 | — | — | WO | disclosed |