SCHEMBL30736787

SCHEMBL30736787

Cc1cc(C)c(C2=C(O)C3(CCC(OC4CCN(CCOCCOCCOCCOCCOCC(=O)OC(C)(C)C)CC4)CC3)OC2=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.34
MEN1 O00255 1/20 0.33
KMT2A Q03164 1/20 0.33
ALDH1A1 P00352 2/20 0.32
HTR7 P34969 1/20 0.32
POLB P06746 2/20 0.31
KDM4E B2RXH2 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
HRH1 P35367 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30736936 1.00 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27378569 1.00 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27377922 1.00 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27378328 1.00 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27378035 1.00 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL30736932 0.92 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL30736983 0.92 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL30736970 0.92 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27380696 0.92 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7
SCHEMBL27380867 0.92 SCN9A (0.34) SCN9AMEN1KMT2AALDH1A1HTR7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed