SCHEMBL30736932

SCHEMBL30736932

Cc1cc(C)c(C2=C(O)C3(CCC(OCCOCCOCCN4CCN(CCOCCOCC(=O)OC(C)(C)C)CC4)CC3)OC2=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SCN9A Q15858 1/20 0.34
HTR7 P34969 5/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
ALDH1A1 P00352 2/20 0.32
HTR1A P08908 4/20 0.32
HTR2A P28223 4/20 0.31
ADRA1A P35348 3/20 0.31
HTR6 P50406 3/20 0.31
DRD2 P14416 2/20 0.31
KDM4E B2RXH2 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30736983 1.00 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL27380696 1.00 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL27380867 1.00 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL30736970 0.98 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL30737032 0.97 SCN9A (0.35) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL27379225 0.97 SCN9A (0.35) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL30737196 0.94 KDM4E (0.34) ALDH1A1KDM4EPOLBHPGDHSD17B10
SCHEMBL30736936 0.92 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL30736787 0.92 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1
SCHEMBL27378569 0.92 SCN9A (0.34) SCN9AHTR7MEN1KMT2AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed