Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CACNA1H | O95180 | 1/20 | 0.56 |
| ▸ | DRD2 | P14416 | 11/20 | 0.54 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.39 |
| ▸ | SUCNR1 | Q9BXA5 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30737230 | 0.92 | CACNA1H (0.60) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL16231598 | 0.90 | DRD2 (0.60) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL32683928 | 0.88 | CACNA1H (0.55) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL30202898 | 0.87 | DRD2 (0.57) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL31301242 | 0.82 | DRD2 (0.63) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL16232049 | 0.82 | DRD2 (0.55) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL30737029 | 0.81 | CACNA1H (0.54) | CACNA1HDRD2SIGMAR1 | |
| SCHEMBL31465614 | 0.81 | DRD2 (0.58) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL31110037 | 0.80 | DRD2 (0.55) | CACNA1HDRD2SIGMAR1MEN1GAA | |
| SCHEMBL15686282 | 0.80 | DRD2 (0.58) | CACNA1HDRD2SIGMAR1MEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4580405-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | Oerth Bio LLC (US) | 2025-07-09 | — | — | EP | disclosed |
| WO-2024050016-A9 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-04-03 | — | — | WO | disclosed |
| WO-2025049555-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2025-03-06 | — | — | WO | disclosed |
| WO-2024050016-A1 | COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL | OERTH BIO LLC (US) | 2024-03-07 | — | — | WO | disclosed |