SCHEMBL30736974

SCHEMBL30736974

COC(=O)COCCCOCCOS(=O)(=O)c1ccc(C)cc1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
STAT3 P40763 2/20 0.44
PSMD10 O75832 1/20 0.42
TBXA2R P21731 2/20 0.42
ALDH1A1 P00352 4/20 0.41
CTDSP1 Q9GZU7 1/20 0.40
SIRT5 Q9NXA8 1/20 0.40
ENPP3 O14638 2/20 0.39
ENPP1 P22413 2/20 0.39
ENPP2 Q13822 2/20 0.39
L3MBTL1 Q9Y468 1/20 0.39
MMP2 P08253 1/20 0.38
MMP9 P14780 1/20 0.38
MMP8 P22894 1/20 0.38
MMP13 P45452 1/20 0.38
CA12 O43570 1/20 0.38
CA1 P00915 1/20 0.38
CA9 Q16790 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38
GLA P06280 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737054 1.00 STAT3 (0.44) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL25199152 0.96 STAT3 (0.47) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL18205492 0.95 STAT3 (0.46) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL21822673 0.95 STAT3 (0.48) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL29084468 0.91 STAT3 (0.45) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL29264617 0.88 PSMD10 (0.43) STAT3PSMD10ALDH1A1CTDSP1SIRT5
SCHEMBL17940871 0.86 TBXA2R (0.51) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL17941061 0.86 STAT3 (0.39) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL18530413 0.86 STAT3 (0.39) STAT3PSMD10TBXA2RALDH1A1CTDSP1
SCHEMBL31425361 0.86 GAA (0.44) STAT3PSMD10TBXA2RALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2025049555-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-03-06 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed