Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.42 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.42 |
| ▸ | PSMD10 | O75832 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP9 | P14780 | 1/20 | 0.40 |
| ▸ | MMP8 | P22894 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | TBXA2R | P21731 | 2/20 | 0.39 |
| ▸ | ENPP3 | O14638 | 2/20 | 0.39 |
| ▸ | ENPP1 | P22413 | 2/20 | 0.39 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21822673 | 0.99 | STAT3 (0.48) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL30736974 | 0.96 | STAT3 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL30737054 | 0.96 | STAT3 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL18205492 | 0.90 | STAT3 (0.46) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL29084468 | 0.89 | STAT3 (0.45) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL21855220 | 0.89 | ALDH1A1 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL3418749 | 0.89 | ALDH1A1 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL23754733 | 0.89 | ALDH1A1 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL21855288 | 0.89 | ALDH1A1 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 | |
| SCHEMBL24624743 | 0.89 | ALDH1A1 (0.44) | STAT3ALDH1A1CTDSP1SIRT5PSMD10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024232597-A1 | 4-CHROMANONE COMPOUNDS THAT DEGRADE WDR5 AND USES THEREOF | 엘젠테라퓨틱스 주식회사 | 2024-11-14 | — | — | WO | disclosed |
| WO-2023090829-A1 | LOW-MOLECULAR-WEIGHT COMPOUND FOR REGULATING MLL1-WDR5 INTERACTION AND USE THEREOF | 엘젠테라퓨틱스 주식회사 | 2023-05-25 | — | — | WO | disclosed |
| WO-2022235699-A2 | POTENT ASGPR-BINDING COMPOUNDS FOR THE DEGRADATION OF IMMUNOGLOBULINS AND OTHER PROTEINS | AVILAR THERAPEUTICS, INC. (US) | 2022-11-10 | — | — | WO | disclosed |