SCHEMBL30737196

SCHEMBL30737196

Cc1cc(C)c(C2=C(O)C3(CCC(OCCOCCOCCOCCOCC(=O)OC(C)(C)C)CC3)OC2=O)c(C)c1

nearest known ligand 0.34

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ALDH1A1 P00352 1/20 0.34
POLB P06746 1/20 0.34
HPGD P15428 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27380867 0.94 SCN9A (0.34) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL30736983 0.94 SCN9A (0.34) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL27380696 0.94 SCN9A (0.34) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL30736932 0.94 SCN9A (0.34) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL30736970 0.92 SCN9A (0.34) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL27379225 0.90 SCN9A (0.35) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL30737032 0.90 SCN9A (0.35) KDM4EALDH1A1POLBHPGDHSD17B10
SCHEMBL27377101 0.88
SCHEMBL30736999 0.88
SCHEMBL27376778 0.88

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4580405-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL Oerth Bio LLC (US) 2025-07-09 EP disclosed
WO-2024050016-A9 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2025-04-03 WO disclosed
WO-2024050016-A1 COMPOSITIONS AND METHODS FOR TARGETED INHIBITION AND DEGRADATION OF PROTEINS IN AN INSECT CELL OERTH BIO LLC (US) 2024-03-07 WO disclosed