SCHEMBL30737248

SCHEMBL30737248

COC(=O)[C@H](CCC(C)(C)C)NCc1ccc(Oc2cccc(OCC(=O)O)c2)nc1

nearest known ligand 0.48

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
SORT1 Q99523 4/20 0.48
GRN P28799 3/20 0.48
EGLN1 Q9GZT9 6/20 0.41
LMNA P02545 2/20 0.41
SIRT2 Q8IXJ6 1/20 0.39
ACACA Q13085 2/20 0.38
FFAR1 O14842 1/20 0.36
ACACB O00763 1/20 0.36
CD274 Q9NZQ7 1/20 0.36
ALDH1A1 P00352 2/20 0.36
GAA P10253 1/20 0.36
MEN1 O00255 1/20 0.36
KMT2A Q03164 1/20 0.36
MAPK1 P28482 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30737126 0.91 SORT1 (0.44) SORT1GRNEGLN1LMNASIRT2
SCHEMBL30737298 0.84 SORT1 (0.67) SORT1GRNEGLN1LMNAACACA
SCHEMBL30737368 0.82 SORT1 (0.42) SORT1GRNEGLN1LMNASIRT2
SCHEMBL27165526 0.81 GRN (0.67) SORT1GRNACACAACACBCD274
SCHEMBL27165675 0.81 GRN (0.67) SORT1GRNACACAACACBCD274
SCHEMBL31601087 0.81 GRN (0.67) SORT1GRNACACAACACBCD274
SCHEMBL31646163 0.74 SORT1 (0.66) SORT1GRNACACAACACBGAA
SCHEMBL31646113 0.73 SORT1 (0.54) SORT1GRNEGLN1LMNAACACA
SCHEMBL30736918 0.73 SORT1 (0.69) SORT1GRNLMNAALDH1A1GAA
SCHEMBL30737105 0.73 SORT1 (0.69) SORT1GRNLMNAALDH1A1GAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed