SCHEMBL30737403

SCHEMBL30737403

COC(=O)COCCOCCCCCCNC(=O)OC(C)(C)C

nearest known ligand 0.56

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ TDP1 Q9NUW8 1/20 0.56
▸ CA12 O43570 6/20 0.53
▸ CA1 P00915 6/20 0.53
▸ CA2 P00918 6/20 0.53
▸ CA9 Q16790 6/20 0.53
▸ MAOA P21397 1/20 0.50
▸ MAOB P27338 1/20 0.50
▸ MEN1 O00255 1/20 0.47
▸ GAA P10253 1/20 0.47
▸ KMT2A Q03164 1/20 0.47
▸ DRD2 P14416 2/20 0.39
▸ EPHX1 P07099 2/20 0.39
▸ CYP3A4 P08684 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19434505 0.88 TDP1 (0.46) TDP1CA12CA1CA2CA9
SCHEMBL17937439 0.88 TDP1 (0.46) TDP1CA12CA1CA2CA9
SCHEMBL28800875 0.88 TDP1 (0.58) TDP1CA12CA1CA2CA9
SCHEMBL30737456 0.87 TDP1 (0.58) TDP1CA12CA1CA2CA9
SCHEMBL21068292 0.86 CA12 (0.52) TDP1CA12CA1CA2CA9
SCHEMBL17286193 0.84 CA12 (0.56) TDP1CA12CA1CA2CA9
SCHEMBL17941165 0.84 CA12 (0.56) TDP1CA12CA1CA2CA9
SCHEMBL14524172 0.84 TDP1 (0.71) TDP1CA12CA1CA2CA9
SCHEMBL22940247 0.84 TDP1 (0.61) TDP1CA12CA1CA2CA9
SCHEMBL5576215 0.84 TDP1 (0.71) TDP1CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2025-11-13 — — US disclosed
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 — — EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250345446-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES SORT1, SCARB1, LAMP1 TDP1 2734/4885CA12 4066/4885CA1 4441/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback