SCHEMBL30737409

SCHEMBL30737409

Cc1cc(-c2ccc(C(=O)OC(C)(C)C)cc2)cc(N)n1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.52
CA1 P00915 1/20 0.52
CA2 P00918 1/20 0.52
CA9 Q16790 1/20 0.52
CA14 Q9ULX7 1/20 0.52
DYRK1A Q13627 1/20 0.42
ABCG2 Q9UNQ0 1/20 0.39
PDK2 Q15119 1/20 0.39
STAT3 P40763 2/20 0.37
ALOX15 P16050 1/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HPGD P15428 1/20 0.37
RXFP1 Q9HBX9 1/20 0.37
MKNK1 Q9BUB5 1/20 0.36
MKNK2 Q9HBH9 1/20 0.36
TP53 P04637 1/20 0.36
GABRA1 P14867 1/20 0.36
GABRG2 P18507 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6350965 0.78 CA12 (0.71) CA12CA1CA2CA9CA14
SCHEMBL8097425 0.77 CA12 (0.66) CA12CA1CA2CA9CA14
SCHEMBL31188361 0.75 MKNK1 (0.59) CA12CA1CA2CA9CA14
SCHEMBL1853389 0.75 CA12 (0.63) CA12CA1CA2CA9CA14
SCHEMBL28663539 0.75 CA12 (0.49) CA12CA1CA2CA9CA14
SCHEMBL453058 0.74 MEN1 (0.47) CA12CA1CA2CA9CA14
SCHEMBL7705962 0.74 CYP1A2 (0.60) CA12CA1CA2CA9CA14
SCHEMBL1954339 0.74 CA12 (0.57) CA12CA1CA2CA9CA14
SCHEMBL2076830 0.73 CA12 (0.65) CA12CA1CA2CA9CA14
SCHEMBL1425511 0.73 CA12 (0.40) CA12CA1CA2CA9CA14

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4543858-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES Draupnir Bio ApS (DK) 2025-04-30 EP disclosed
WO-2023247754-A1 BIFUNCTIONAL MOLECULES THAT SELECTIVELY INDUCE DEGRADATION OF EXTRACELLULAR TARGETS IN LYSOSOMES DRAUPNIR BIO APS (DK) 2023-12-28 WO disclosed