Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 3/20 | 0.66 |
| ▸ | CA1 | P00915 | 3/20 | 0.66 |
| ▸ | CA2 | P00918 | 3/20 | 0.66 |
| ▸ | CA9 | Q16790 | 3/20 | 0.66 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | MAOA | P21397 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.45 |
| ▸ | ADRB2 | P07550 | 2/20 | 0.44 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.44 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.44 |
| ▸ | PHLPP2 | Q6ZVD8 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL380152 | 0.94 | CA12 (0.57) | CA12CA1CA2CA9CA14 | |
| Methane SCHEMBL28278848 | 0.92 | CA12 (0.56) | CA12CA1CA2CA9CA14 | |
| Nitrogen SCHEMBL27824368 | 0.91 | CA12 (0.54) | CA12CA1CA2CA9CA14 | |
| SCHEMBL6350965 | 0.90 | CA12 (0.71) | CA12CA1CA2CA9CA14 | |
| Acetic Acid SCHEMBL5239675 | 0.89 | CA12 (0.53) | CA12CA1CA2CA9CA14 | |
| SCHEMBL2076830 | 0.85 | CA12 (0.65) | CA12CA1CA2CA9CA14 | |
| Formic Acid Methyl Ester SCHEMBL28278877 | 0.84 | CA12 (0.49) | CA12CA1CA2CA9CA14 | |
| Hydrazine SCHEMBL10771056 | 0.84 | CA12 (0.62) | CA12CA1CA2CA9CA14 | |
| SCHEMBL109451 | 0.84 | CA1 (0.61) | CA12CA1CA2CA9CA14 | |
| SCHEMBL8097492 | 0.84 | CA12 (0.49) | CA12CA1CA2CA9CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4695226-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | Pfizer Inc. (US) | 2026-02-18 | — | — | EP | disclosed |
| US-20240366598-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2024-11-07 | — | — | US | disclosed |
| WO-2024214038-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | PFIZER INC. (US) | 2024-10-17 | — | — | WO | disclosed |
| US-6011175-A | Inhibition of farnesyltransferase | UNIVERSITY OF PITTSBURGH (US) | 2000-01-04 | — | — | US | disclosed |
| US-5965539-A | PEPTIDOMIMETICS; ANTI-CANCER DRUGS | UNIVERISTY OF PITTSBURGH (US) | 1999-10-12 | — | — | US | disclosed |
| EP-0794789-A4 | INHIBITORS OF PRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 1999-05-26 | — | — | EP | disclosed |
| US-5705686-A | 3-MERCAPTO-2-AMINO-PROPYLAMINOBIPHENYL DERIVATIVES; PEPTIDOMIMETICS; ANTICARCINOGENIC AGENTS | UNIVERSITY OF PITTSBURGH (US) | 1998-01-06 | — | — | US | disclosed |
| EP-0794789-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1997-09-17 | — | — | EP | disclosed |
| WO-1996021456-A1 | INHIBITORS OF PRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240366598-A1 | GLUCOSE-DEPENDENT INSULINOTROPIC POLYPEPTIDE RECEPTOR ANTAGONISTS AND USES THEREOF | GIPR, GLP1R, GPR119 | CA12 3264/4885CA1 2418/4885CA2 1254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.