Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 2/20 | 0.79 |
| ▸ | CA1 | P00915 | 2/20 | 0.65 |
| ▸ | CA2 | P00918 | 2/20 | 0.65 |
| ▸ | CA12 | O43570 | 1/20 | 0.65 |
| ▸ | CA9 | Q16790 | 1/20 | 0.65 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.62 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.62 |
| ▸ | CDK1 | P06493 | 1/20 | 0.62 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.62 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.62 |
| ▸ | CDK2 | P24941 | 1/20 | 0.62 |
| ▸ | CDK7 | P50613 | 1/20 | 0.62 |
| ▸ | CCNH | P51946 | 1/20 | 0.62 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.62 |
| ▸ | TCF4 | P15884 | 1/20 | 0.59 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.59 |
| ▸ | POLB | P06746 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9763115 | 1.00 | HTR6 (0.79) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL28270292 | 0.89 | HTR6 (0.71) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL28271812 | 0.88 | HTR6 (1.00) | HTR6CA1CA2CA9POLB | |
| SCHEMBL14877794 | 0.88 | CA12 (0.76) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL16199439 | 0.86 | HTR6 (0.71) | HTR6CA1CA2POLBKMT2A | |
| SCHEMBL3701951 | 0.85 | CA12 (0.71) | CA1CA2CA12CA9FFAR4 | |
| SCHEMBL2723618 | 0.85 | HTR6 (1.00) | HTR6CA1CA2FFAR4POLB | |
| SCHEMBL28271804 | 0.84 | HTR6 (0.69) | HTR6CA1CA2POLBGAA | |
| SCHEMBL2240551 | 0.84 | HTR6 (0.73) | HTR6CA1CA2CA12CA9 | |
| SCHEMBL30737524 | 0.84 | HTR6 (0.79) | HTR6CA1CA2FFAR4FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117510460-A | Benzo [ b ] thiophene derivative containing sulfonamide unit, and preparation method and application thereof | 贵州大学 | 2024-02-06 | — | — | CN | disclosed |