Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 20/20 | 1.00 |
| ▸ | KDR | P35968 | 18/20 | 1.00 |
| ▸ | FGFR2 | P21802 | 12/20 | 1.00 |
| ▸ | FGFR4 | P22455 | 12/20 | 1.00 |
| ▸ | FGFR3 | P22607 | 12/20 | 1.00 |
| ▸ | FLT1 | P17948 | 10/20 | 0.68 |
| ▸ | FLT4 | P35916 | 10/20 | 0.68 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | SRC | P12931 | 1/20 | 0.49 |
| ▸ | CSK | P41240 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27218125 | 1.00 | FGFR1 (1.00) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL6056003 | 0.82 | FGFR1 (0.70) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL16868903 | 0.80 | FGFR1 (1.00) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL26928630 | 0.79 | FGFR1 (1.00) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL6640513 | 0.78 | FGFR1 (0.66) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL6639949 | 0.77 | FGFR1 (0.63) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL6916832 | 0.77 | FGFR1 (0.63) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL20943051 | 0.70 | FGFR1 (0.75) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL31647879 | 0.69 | FGFR1 (0.52) | FGFR1KDRFGFR2FGFR4FGFR3 | |
| SCHEMBL8147144 | 0.68 | FGFR1 (0.56) | FGFR1KDRFGFR2FGFR4FGFR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | claimed |
| WO-2023240271-A1 | USE OF VEGFR2 AND FGFR1 INHIBITORS IN THERAPY | FOUNTAIN THERAPEUTICS INC. (US) | 2023-12-14 | — | — | WO | disclosed |