SCHEMBL31647879

SCHEMBL31647879

CCCCCNc1ccc2cc(-c3cc(OC)cc(OC)c3)c(N)nc2n1

nearest known ligand 0.52

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
▸ FGFR1 P11362 15/20 0.52
▸ KDR P35968 12/20 0.52
▸ FGFR2 P21802 9/20 0.52
▸ FGFR4 P22455 9/20 0.52
▸ FGFR3 P22607 9/20 0.52
▸ TLR8 Q9NR97 4/20 0.37
▸ FLT1 P17948 7/20 0.36
▸ FLT4 P35916 7/20 0.36
▸ GLA P06280 1/20 0.35
▸ SRC P12931 1/20 0.35
▸ CSK P41240 1/20 0.35
▸ KMT2A Q03164 1/20 0.35
▸ ATM Q13315 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31648011 0.89 FGFR1 (0.49) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647959 0.86 FGFR1 (0.46) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647914 0.86 FGFR1 (0.46) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647773 0.85 PTGDR (0.50) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648220 0.83 FGFR1 (0.44) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648041 0.81 TLR8 (0.41) TLR8
SCHEMBL31647779 0.80 FGFR1 (0.40) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31648474 0.78 FGFR1 (0.48) FGFR1KDRFGFR2FGFR4FGFR3
SCHEMBL31647883 0.76 TLR8 (0.43) FGFR1TLR8
SCHEMBL31648364 0.73 FGFR1 (0.60) FGFR1KDRFGFR2FGFR4FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025133660-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
WO-2025132449-A1 NOVEL COMPOUNDS FOR HOST DIRECTED ANTIVIRAL STRATEGY SORBONNE UNIVERSITE (FR) 2025-06-26 — — WO disclosed
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