Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | CDK9 | P50750 | 1/20 | 0.53 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 3/20 | 0.50 |
| ▸ | RAB9A | P51151 | 3/20 | 0.50 |
| ▸ | GSK3B | P49841 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.49 |
| ▸ | CNR1 | P21554 | 1/20 | 0.49 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31582377 | 0.81 | POLB (0.66) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL31582535 | 0.78 | POLB (0.67) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL31582291 | 0.77 | POLB (0.65) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL10812814 | 0.75 | GAA (0.45) | POLBALDH1A1SMN1; SMN2KDM4EGAA | |
| SCHEMBL9613322 | 0.74 | PTPN7 (0.67) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| Diphenylurea SCHEMBL133103 | 0.73 | SMN1; SMN2 (1.00) | SMN1; SMN2LMNATP53EPHX1TSHR | |
| SCHEMBL11272208 | 0.72 | GAA (0.60) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL19757532 | 0.72 | POLB (0.54) | POLBALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL5359926 | 0.72 | SMN1; SMN2 (0.77) | SMN1; SMN2TP53EPHX1TSHREPHX2 | |
| Diphenylurea SCHEMBL3037927 | 0.71 | SMN1; SMN2 (0.94) | SMN1; SMN2LMNATP53EPHX1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166119-B | Substituted aryl compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |