Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SOS1 | Q07889 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.36 |
| ▸ | SIRT6 | Q8N6T7 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.34 |
| ▸ | CA1 | P00915 | 2/20 | 0.34 |
| ▸ | CA2 | P00918 | 2/20 | 0.34 |
| ▸ | CA7 | P43166 | 2/20 | 0.34 |
| ▸ | CA9 | Q16790 | 2/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.34 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.34 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21585802 | 1.00 | SOS1 (0.44) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL29165250 | 0.94 | SOS1 (0.41) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL16637297 | 0.87 | SOS1 (0.44) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL31394743 | 0.83 | SOS1 (0.51) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL31739075 | 0.83 | SOS1 (0.40) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL365953 | 0.81 | SOS1 (0.50) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL31079873 | 0.81 | SOS1 (0.50) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL31254604 | 0.81 | SOS1 (0.41) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL24803082 | 0.79 | SOS1 (0.40) | SOS1LMNATSHRNPSR1NR4A2 | |
| SCHEMBL20571340 | 0.78 | SOS1 (0.48) | SOS1LMNATSHRNPSR1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112204028-B | tetrahydro-1H-pyrazino [2,1-a ] isoindoloquinoline compounds for use in the treatment of autoimmune diseases | 豪夫迈·罗氏有限公司 | 2023-12-29 | — | — | CN | disclosed |