Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.53 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.52 |
| ▸ | EP300 | Q09472 | 1/20 | 0.48 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.47 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.47 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.47 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.47 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.47 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.47 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.47 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.47 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31176327 | 0.86 | BTK (0.45) | CETPSOAT1HDAC6KMT2AALDH1A1 | |
| SCHEMBL9504171 | 0.83 | CETP (0.58) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL30276310 | 0.82 | CYP2C19 (0.47) | HDAC6TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL30276290 | 0.82 | CYP2C19 (0.47) | HDAC6TSHRKMT2AALDH1A1MEN1 | |
| SCHEMBL20367701 | 0.81 | HDAC1 (0.54) | CETPSOAT1HDAC3HDAC1HDAC2 | |
| SCHEMBL5010196 | 0.81 | CETP (0.63) | CETPSOAT1TSHRKMT2AALDH1A1 | |
| SCHEMBL5295250 | 0.80 | CETP (0.53) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL30102565 | 0.79 | CETP (0.54) | CETPSOAT1EP300TSHRKMT2A | |
| SCHEMBL28926989 | 0.79 | CETP (0.57) | CETPSOAT1TSHRKMT2AALDH1A1 | |
| SCHEMBL30091845 | 0.79 | CETP (0.52) | CETPSOAT1EP300HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114890990-B | Compound and application thereof in preparation of NAMPT protein autophagy degradation agent | 中国人民解放军海军军医大学 | 2024-01-16 | — | — | CN | disclosed |