Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 2/20 | 0.58 |
| ▸ | SOAT1 | P35610 | 2/20 | 0.53 |
| ▸ | EP300 | Q09472 | 1/20 | 0.49 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.48 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.48 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.48 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.48 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.48 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.48 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.48 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30738545 | 0.83 | CETP (0.53) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL5010196 | 0.82 | CETP (0.63) | CETPSOAT1TSHRKMT2AALDH1A1 | |
| SCHEMBL30102565 | 0.80 | CETP (0.54) | CETPSOAT1EP300TSHRKMT2A | |
| SCHEMBL28926989 | 0.80 | CETP (0.57) | CETPSOAT1TSHRKMT2AALDH1A1 | |
| SCHEMBL30091845 | 0.80 | CETP (0.52) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL14282873 | 0.78 | CETP (0.53) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL9395051 | 0.78 | CETP (0.77) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL5878480 | 0.78 | CETP (0.77) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL9501914 | 0.77 | KMT2A (0.57) | CETPSOAT1EP300HDAC3HDAC1 | |
| SCHEMBL24074514 | 0.76 | CETP (0.65) | CETPSOAT1EP300HDAC3HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543865-A1 | BENZAMIDE DERIVATIVES | RHONE-POULENC RORER LIMITED (GB) | 1993-06-02 | — | — | EP | disclosed |