Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC34A1 | Q06495 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.37 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.37 |
| ▸ | FEN1 | P39748 | 1/20 | 0.37 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.37 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22179708 | 1.00 | SLC34A1 (0.40) | SLC34A1MAP4K4GRM2ALOX5APFEN1 | |
| SCHEMBL30738414 | 0.91 | MAP4K4 (0.39) | SLC34A1MAP4K4GRM2HDAC2HDAC1 | |
| SCHEMBL30738308 | 0.91 | MAP4K4 (0.39) | SLC34A1MAP4K4GRM2HDAC2HDAC1 | |
| SCHEMBL22179710 | 0.91 | MAP4K4 (0.39) | SLC34A1MAP4K4GRM2HDAC2HDAC1 | |
| SCHEMBL28591475 | 0.91 | MAP4K4 (0.39) | SLC34A1MAP4K4GRM2HDAC2HDAC1 | |
| SCHEMBL22179942 | 0.91 | MAP4K4 (0.39) | SLC34A1MAP4K4GRM2HDAC2HDAC1 | |
| SCHEMBL22179959 | 0.87 | HDAC1 (0.46) | MAP4K4GRM2HDAC2HDAC1DYRK1A | |
| SCHEMBL30738352 | 0.87 | HDAC1 (0.46) | MAP4K4GRM2HDAC2HDAC1DYRK1A | |
| SCHEMBL22180265 | 0.86 | ABL1 (0.47) | HDAC2HDAC1KCNH2 | |
| SCHEMBL30738323 | 0.86 | ABL1 (0.47) | HDAC2HDAC1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166119-B | Substituted aryl compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |