Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 1/20 | 0.47 |
| ▸ | ATM | Q13315 | 6/20 | 0.45 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.41 |
| ▸ | KIT | P10721 | 2/20 | 0.41 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | CLK4 | Q9HAZ1 | 1/20 | 0.39 |
| ▸ | PDGFRB | P09619 | 2/20 | 0.39 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | MTOR | P42345 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22180265 | 1.00 | ABL1 (0.47) | ABL1ATMCDK6KITRPS6KA3 | |
| SCHEMBL30738352 | 0.91 | HDAC1 (0.46) | ABL1KITMEN1ALDH1A1LMNA | |
| SCHEMBL22179959 | 0.91 | HDAC1 (0.46) | ABL1KITMEN1ALDH1A1LMNA | |
| SCHEMBL22179962 | 0.88 | SSTR2 (0.40) | ATMPDGFRBPIK3CDPIK3CAHDAC1 | |
| SCHEMBL30738220 | 0.88 | SSTR2 (0.40) | ATMPDGFRBPIK3CDPIK3CAHDAC1 | |
| SCHEMBL22179957 | 0.87 | ALDH1A1 (0.38) | ABL1ATMALDH1A1PDGFRBHDAC1 | |
| SCHEMBL30738266 | 0.87 | ALDH1A1 (0.38) | ABL1ATMALDH1A1PDGFRBHDAC1 | |
| SCHEMBL30738554 | 0.86 | SLC34A1 (0.40) | KCNH2HDAC1HDAC2 | |
| SCHEMBL22179708 | 0.86 | SLC34A1 (0.40) | KCNH2HDAC1HDAC2 | |
| SCHEMBL22179942 | 0.85 | MAP4K4 (0.39) | ABL1LMNATSHRKCNH2HDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113166119-B | Substituted aryl compound and preparation method and application thereof | 四川科伦博泰生物医药股份有限公司 | 2024-01-05 | — | — | CN | disclosed |