Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLKB1 | P03952 | 20/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL369754 | 0.86 | KLKB1 (0.52) | KLKB1 | |
| SCHEMBL31352716 | 0.86 | KLKB1 (0.52) | KLKB1 | |
| SCHEMBL17786840 | 0.82 | KLKB1 (0.66) | KLKB1 | |
| SCHEMBL17786902 | 0.80 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL17786838 | 0.80 | KLKB1 (0.47) | KLKB1 | |
| SCHEMBL17784845 | 0.79 | KLKB1 (0.78) | KLKB1 | |
| SCHEMBL22491826 | 0.78 | KLKB1 (0.65) | KLKB1 | |
| SCHEMBL26227494 | 0.78 | KLKB1 (0.46) | KLKB1 | |
| SCHEMBL22981211 | 0.77 | KLKB1 (0.45) | KLKB1 | |
| Bicarbonate SCHEMBL17785352 | 0.76 | KLKB1 (0.73) | KLKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |