Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | CYP1A1 | P04798 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | CYP1B1 | Q16678 | 2/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CSNK2A1 | P68400 | 2/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.34 |
| ▸ | ATP4A | P20648 | 1/20 | 0.33 |
| ▸ | ATP4B | P51164 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 1/20 | 0.32 |
| ▸ | SRC | P12931 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1716296 | 1.00 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL1945874 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29809738 | 0.87 | ALDH1A1 (0.56) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL27783461 | 0.82 | ALDH1A1 (0.44) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL8763318 | 0.80 | ALDH1A1 (0.50) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL29382225 | 0.79 | TSHR (0.50) | ALDH1A1CYP1A1CYP1A2CYP1B1TRPA1 | |
| SCHEMBL28289 | 0.79 | TSHR (0.50) | ALDH1A1CYP1A1CYP1A2CYP1B1TRPA1 | |
| SCHEMBL24176025 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL3917506 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 | |
| SCHEMBL860437 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDCYP1A1CYP1A2CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4561993-A1 | INHIBITORS OF PLASMA KALLIKREIN | Rezolute, Inc. (US) | 2025-06-04 | — | — | EP | disclosed |
| CN-120051460-A | Plasma kallikrein inhibitors | 瑞泽路特有限公司 | 2025-05-27 | — | — | CN | disclosed |
| CN-119954712-A | Compound containing phenoxynaphthalene and preparation method and application thereof | 四川轻化工大学 | 2025-05-09 | — | — | CN | disclosed |
| WO-2024025907-A1 | INHIBITORS OF PLASMA KALLIKREIN | REZOLUTE, INC. (US) | 2024-02-01 | — | — | WO | disclosed |