Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 4/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.43 |
| ▸ | ESRRA | P11474 | 2/20 | 0.34 |
| ▸ | MIF | P14174 | 2/20 | 0.32 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.30 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.30 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29178645 | 1.00 | ESR1 (0.43) | ESR1ESR2ESRRAMIFCAPN1 | |
| SCHEMBL29178941 | 0.86 | ESR1 (0.41) | ESR1ESR2ESRRACAPN1 | |
| SCHEMBL1014014 | 0.68 | ESRRA (0.39) | ESR1ESR2ESRRACAPN1 | |
| SCHEMBL1014457 | 0.66 | ESRRA (0.45) | ESR1ESR2ESRRACAPN1 | |
| SCHEMBL4287549 | 0.64 | KDR (0.43) | — | |
| SCHEMBL4274776 | 0.64 | ESR1 (0.44) | ESR1ESR2ESRRAMIFCAPN1 | |
| SCHEMBL16720493 | 0.63 | ESR1 (0.35) | ESR1ESR2ESRRAMIFCAPN1 | |
| SCHEMBL1727305 | 0.63 | HSD17B1 (0.43) | ESR1ESR2ESRRACAPN1 | |
| SCHEMBL1014234 | 0.63 | ESRRA (0.39) | ESR1ESR2ESRRACAPN1THRB | |
| SCHEMBL1017182 | 0.63 | ESRRA (0.39) | ESR1ESR2ESRRACAPN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |