Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | EGFR | P00533 | 7/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 2/20 | 0.34 |
| ▸ | PDE5A | O76074 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | CDK1 | P06493 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739203 | 0.92 | KMT2A (0.39) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL29178641 | 0.82 | EGFR (0.41) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL30739262 | 0.79 | MEN1 (0.38) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL30739398 | 0.78 | PDE5A (0.36) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL30739402 | 0.77 | MAP4K4 (0.37) | — | |
| SCHEMBL30739323 | 0.77 | MAP4K4 (0.36) | — | |
| SCHEMBL30739354 | 0.76 | PDE5A (0.35) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL30739343 | 0.76 | EGFR (0.39) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL29178699 | 0.76 | EGFR (0.39) | KMT2AMEN1EGFRPOLBNR2F2 | |
| SCHEMBL30739372 | 0.76 | MAP4K4 (0.40) | L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |