Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP4K4 | O95819 | 3/20 | 0.37 |
| ▸ | PIK3CD | O00329 | 3/20 | 0.32 |
| ▸ | TNK2 | Q07912 | 2/20 | 0.31 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.31 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.30 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.30 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30739323 | 0.90 | MAP4K4 (0.36) | MAP4K4PIK3CDTNK2PDE4BPDE4D | |
| SCHEMBL30739372 | 0.89 | MAP4K4 (0.40) | MAP4K4PIK3CDTNK2PDE4BPDE4D | |
| SCHEMBL30739203 | 0.83 | KMT2A (0.39) | — | |
| SCHEMBL30739376 | 0.83 | BRD4 (0.40) | — | |
| SCHEMBL30739393 | 0.80 | MAP4K4 (0.32) | MAP4K4PIK3CD | |
| SCHEMBL30739280 | 0.77 | KMT2A (0.39) | — | |
| SCHEMBL30739427 | 0.76 | BRD4 (0.42) | — | |
| SCHEMBL30739145 | 0.74 | TEK (0.37) | MAP4K4 | |
| SCHEMBL30739237 | 0.74 | BLK (0.39) | MAP4K4 | |
| SCHEMBL30366632 | 0.66 | KDM4E (0.40) | MAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117466897-A | Highly selective FGFR2 inhibitors | 深圳福沃药业有限公司 | 2024-01-30 | — | — | CN | disclosed |