Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | BCHE | P06276 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | MAOB | P27338 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | BACE1 | P56817 | 1/20 | 0.42 |
| ▸ | MGAM | O43451 | 1/20 | 0.42 |
| ▸ | CNR2 | P34972 | 1/20 | 0.42 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.42 |
| ▸ | PGR | P06401 | 1/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27963663 | 1.00 | MAPT (0.45) | MAPTLMNANPC1BCHERAB9A | |
| SCHEMBL3275092 | 0.89 | PTGER3 (0.53) | MAPTLMNAPPARGPPARACNR2 | |
| SCHEMBL29396289 | 0.88 | NPC1 (0.52) | MAPTLMNANPC1BCHERAB9A | |
| SCHEMBL3307087 | 0.88 | NPC1 (0.52) | MAPTLMNANPC1BCHERAB9A | |
| SCHEMBL9369351 | 0.88 | NPC1 (0.52) | MAPTLMNANPC1BCHERAB9A | |
| SCHEMBL6417786 | 0.86 | NPC1 (0.39) | MAPTLMNANPC1BCHERAB9A | |
| SCHEMBL28852820 | 0.81 | PPARG (0.62) | MAPTPPARGPPARAPGRHTR1A | |
| SCHEMBL4822382 | 0.81 | PPARG (0.62) | MAPTPPARGPPARAPGRHTR1A | |
| SCHEMBL4822390 | 0.81 | PPARG (0.62) | MAPTPPARGPPARAPGRHTR1A | |
| SCHEMBL27706696 | 0.78 | MAPT (0.58) | MAPTLMNABCHEPPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113354609-B | Isopentenyl substituted coumarin compound and preparation method and application thereof | 海南师范大学 | 2024-04-05 | — | — | CN | disclosed |
| CN-113321695-B | Steroid compound, and preparation method and application thereof | 海南师范大学 | 2024-01-12 | — | — | CN | disclosed |